Publications

2026

 

Conserved transcriptional co-regulation of pyrophosphate homeostasis genes governs systemic mineralization factors in mice and humans. V. Tamatey, M. Várhegyi, B. Blaha, J.V. Wynsberghe, L. Lion, Z. Ahmadi, D. Juhász, E. Bata, D.T. Márton, M. Muhyiddeen, A.I. Nagy, C.P. Martinez-Jimenez, O. Vanakker, T. Arányi# and F. Szeri†#. - Molecular Metabolism, in press

 

 

Setdb1 safeguards proper differentiation of adult intestinal stem cells by controlling chromatin accessibility and transcriptome variability.  I. Peraki*, L. Zhang*, D. Botskaris*, M Stagaki*, IK. Deligiannis*, H. Kontaki,

E.. Deligianni, I .Giannoulakis, O. Hazapis, MD. Lavigne#, CP. Martinez-Jimenez# and I Talianidis#  - iSCIENCE, 2026 in press

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2025

 

Hepatic metabolic reprogramming in male mice during short-term caloric restriction involves enhanced glucocorticoid rhythms. K Makris, V Fonda, FF Ramadhani, ..., Ioannis K Deligiannis, Liwei Zhang, ... Celia P Martinez-Jimenez, Fabiana Quagliarini*, N Henriette Uhlenhaut* - Nature Communications, 2025

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Preclinical evaluation of human ABCB5+ skin-derived stem cells reveals regenerative mechanisms and prognostic markers in a novel ACLF mouse model. L Neckermann, P Erdösi, L Zhang, ... M Menden, C Martinez-Jimenez, S Hammad - Zeitschrift für Gastroenterologie, 2025

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2024

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Spatial Transcriptomics Identifies Novel Clinical Markers to Classify the Etiology of Rare and Aggressive Cardiac Sarcomas

L Zhang, D Yuan, M Dong, Y Cai, S-H Jin, B Frey, U Gaipl, P Sun, CP Martinez-Jimenez*, J Wang*, H Ma*, J-G Zhou*. Circulation, 2024 (Abstract 4136692)

 

Setdb1 regulates proper differentiation of adult intestinal stem cells via restraining permissive chromatin structure and transcriptional variability

D Botskaris, I Deligiannis, I Peraki… CP. Martinez-Jimenez*, I Talianidis* - bioRxiv, 2024

 

Polyploidisation pleiotropically buffers ageing in hepatocytes

K Yin, M Büttner, IK Deligiannis, M Strzelecki, L Zhang, C Talavera-Lopez, F Theis*, DT Odom*, CP Martinez-Jimenez*. Journal of Hepatology, 2024

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2023

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Single-cell metabolic profiling reveals subgroups of primary human hepatocytes with heterogeneous responses to drug challenge

E Sanchez-Quant, ML Richter,… CP Martinez-Jimenez.  Genome Biology, 2023, 24 (1), 234

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Multi-omics and 3D-imaging reveal bone heterogeneity and unique calvaria cells in neuroinflammation

Zeynep Ilgin Kolabas, Louis B. Kuemmerle, Robert Perneczky, Benjamin Förstera, ... Ioannis K. Deligiannis, Celia P. Martinez-Jimenez..., Ali Erturk. Cell 2023, 186 (17), 3706-3725. e29 

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Spatial transcriptomics using multiplexed deterministic barcoding in tissue

J Wirth, N Compera, K Yin, S Brood, S Chang, CP Martinez-Jimenez*, M. Meier*.

Nature Communications 2023, 14 (1), 1523

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High-calorie diets uncouple hypothalamic oxytocin neurons from a gut-to-brain satiation pathway via κ-opioid signaling

T Gruber, F Lechner, C Murat,..., CP Martinez-Jimenez, MH Tschoep, V Grinevich, C Garcia-Caceres.

Cell Reports 2023, 42 (10)

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Interleukin 6 and interferon gamma haplotypes are related to cytokine serum levels in dogs in an endemic Leishmania infantum region

Luis Álvarez, Pablo-Jesús Marín-García, Pilar Rentero-Garrido, Celia Pilar Martinez-Jimenez, Lola Llobat.

Infectious Diseases of Poverty 2023, 12 (01), 62-70

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2022

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Coupling of oxytocin and cholecystokinin pathways in the hypothalamus is required for gut-to-brain homeostatic feeding control

T Gruber, F Lechner, C Murat,..., CP Martinez-Jimenez, MH Tschoep, V Grinevich, C Garcia-Caceres.

bioRxiv, 2022.07. 20.500778

 

Isolation of Nuclei from Flash-frozen Liver Tissue for Single-cell Multiomics.

M Strzelecki, K Yin, C Talavera-López, CP Martinez-Jimenez.

Journal of Visualized Experiments: Jove,  2022, e64792